Ochlocknee, is a small agricultural community located in the northwest quad-rant of Thomas County, settled in the early 1830’s, although 1860 is the accepted year of inception. The name is derivative of the river that flows through it, the Ochlocknee River, which is a Native American term meaning “crooked waters.” Agriculture is the primary economic engine of Ochlocknee, where an extraordinary variety of crops have been grown. While the Ochlocknee River is usually too narrow and shallow for the movement of mass commodities, the construction of the railroad that connected Thomasville to Albany via Ochlocknee in 1869 provided the farmers with a way to get their goods to markets.

By 1915, a group called the Ochlocknee Boosters successfully lobbied to have a portion of the unwieldy Dixie Highway built through their section. Construction took four years, and included a new large bridge spanning the Ochlocknee River at the cost of $56,000. Through the twentieth century, Ochlocknee developed all the private, civic and municipal organizations one might expect. Just North of the community is Oil-Dri Corporation, an essential member of this agrarian community. Oil-Dri is a world leader in premium absorbent products. It is a region employer. Never having grown too small to lose its charter or too large to lose its character, Ochlocknee remains a traditional agricultural community in both practice and spirit.